# Oral Vancomycin Versus Probiotics Versus Placebo for Prevention of Clostridium Difficile Infection in Colonized Patients

> **NCT04246151** · EARLY_PHASE1 · WITHDRAWN · sponsor: **Hamilton Health Sciences Corporation**

## Conditions studied

- Clostridium Difficile Colonization
- Clostridium Difficile Diarrhea

## Interventions

- **DRUG:** Vancomycin
- **DIETARY_SUPPLEMENT:** Culturelle
- **DRUG:** Vancomycin Placebo
- **DRUG:** Probiotic Placebo

## Key facts

- **NCT ID:** NCT04246151
- **Lead sponsor:** Hamilton Health Sciences Corporation
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-09-01
- **Primary completion:** 2024-09-12
- **Final completion:** 2024-09-12
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** No patients enrolled. Identification of patients in allocated timeframe was not feasible.
- **Last updated:** 2025-02-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04246151

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04246151, "Oral Vancomycin Versus Probiotics Versus Placebo for Prevention of Clostridium Difficile Infection in Colonized Patients". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04246151. Licensed CC0.

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