# Preoperative Systemic Therapy vs Upfront Surgery in HER2 Positive Early Breast Cancer

> **NCT04249440** · — · COMPLETED · sponsor: **Zhejiang Cancer Hospital** · enrollment: 1067 (actual)

## Conditions studied

- Breast Cancer
- HER2
- Preoperative Systemic Treatment

## Interventions

- **PROCEDURE:** Preoperative systemic treatment

## Key facts

- **NCT ID:** NCT04249440
- **Lead sponsor:** Zhejiang Cancer Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2012-01-01
- **Primary completion:** 2019-12-30
- **Final completion:** 2020-03-30
- **Target enrollment:** 1067 (ACTUAL)
- **Last updated:** 2020-09-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04249440

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04249440, "Preoperative Systemic Therapy vs Upfront Surgery in HER2 Positive Early Breast Cancer". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04249440. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
