# A Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).

> **NCT04251494** · — · UNKNOWN · sponsor: **Guy's and St Thomas' NHS Foundation Trust** · enrollment: 32 (estimated)

## Conditions studied

- Phenylketonurias
- Cardiovascular Diseases

## Interventions

- **DIAGNOSTIC_TEST:** Carotid intima media thickness measurement (CIMT)
- **DIAGNOSTIC_TEST:** Pulse Wave Velocity measurement
- **DIAGNOSTIC_TEST:** Ankle-brachial pressure index (ABPI)
- **OTHER:** Diet questionnaire and diet diary
- **OTHER:** Routine blood samples

## Key facts

- **NCT ID:** NCT04251494
- **Lead sponsor:** Guy's and St Thomas' NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-02-23
- **Primary completion:** 2021-04-22
- **Final completion:** 2021-04-22
- **Target enrollment:** 32 (ESTIMATED)
- **Last updated:** 2020-07-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04251494

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04251494, "A Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04251494. Licensed CC0.

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