# The Effect of Intravenous Mannitol Plus Saline on the Prevention of Cisplatin-induced Nephrotoxicity: A Randomized, Double-blind, Placebo Controlled Trial

> **NCT04251689** · PHASE2,PHASE3 · COMPLETED · sponsor: **Phramongkutklao College of Medicine and Hospital** · enrollment: 48 (actual)

## Conditions studied

- Cis-Platinum Nephropathy
- Mannitol Adverse Reaction

## Interventions

- **DRUG:** Mannitol
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04251689
- **Lead sponsor:** Phramongkutklao College of Medicine and Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-12-01
- **Primary completion:** 2020-07-01
- **Final completion:** 2021-02-14
- **Target enrollment:** 48 (ACTUAL)
- **Last updated:** 2022-01-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04251689

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04251689, "The Effect of Intravenous Mannitol Plus Saline on the Prevention of Cisplatin-induced Nephrotoxicity: A Randomized, Double-blind, Placebo Controlled Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04251689. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*