mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

NCT04251715 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

5

Enrollment

OTHER

Sponsor class

Conditions

Liver and Intrahepatic Bile Duct Carcinoma
Stage III Intrahepatic Cholangiocarcinoma AJCC v8
Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8
Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8
Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Unresectable Intrahepatic Cholangiocarcinoma

Interventions

DRUG: Dexamethasone
DRUG: Floxuridine
DEVICE: Implanted Medical Device
DRUG: Irinotecan
DRUG: Leucovorin
DRUG: Oxaliplatin
OTHER: Quality-of-Life Assessment

Sponsor

OHSU Knight Cancer Institute

Collaborators

[object Object]