CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

NCT04266249 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

2175

Enrollment

NETWORK

Sponsor class

Conditions

Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Anatomic Stage IIB Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Invasive Breast Carcinoma
Prognostic Stage II Breast Cancer AJCC v8
Prognostic Stage IIA Breast Cancer AJCC v8
Prognostic Stage IIB Breast Cancer AJCC v8
Prognostic Stage IIIA Breast Cancer AJCC v8

Interventions

DRUG: Docetaxel
PROCEDURE: Lumpectomy
PROCEDURE: Mastectomy
DRUG: Nab-paclitaxel
DRUG: Paclitaxel
BIOLOGICAL: Pertuzumab
RADIATION: Radiation Therapy
BIOLOGICAL: Trastuzumab
BIOLOGICAL: Trastuzumab Emtansine

Sponsor

ECOG-ACRIN Cancer Research Group

Collaborators

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