# Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study

> **NCT04278118** · NA · RECRUITING · sponsor: **Emory University** · enrollment: 70 (estimated)

## Conditions studied

- Grade I Meningioma
- Grade II Meningioma
- Grade III Meningioma
- Intracranial Neoplasm
- Nerve Sheath Neoplasm
- Pituitary Gland Adenoma
- Schwannoma

## Interventions

- **RADIATION:** Hypofractionated Radiation Therapy
- **RADIATION:** Photon Beam Radiation Therapy
- **RADIATION:** Proton Beam Radiation Therapy
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT04278118
- **Lead sponsor:** Emory University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-02-18
- **Primary completion:** 2030-12-01
- **Final completion:** 2031-12-01
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2026-02-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04278118

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04278118, "Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study". Retrieved via AI Analytics 2026-07-09 from https://api.ai-analytics.org/clinical/NCT04278118. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*