# Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity

> **NCT04298203** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **University of Minnesota** · enrollment: 100 (actual)

## Conditions studied

- Obesity

## Interventions

- **DRUG:** Phentermine-Topiramate
- **DIETARY_SUPPLEMENT:** Meal Replacement Therapy
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04298203
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2021-08-04
- **Primary completion:** 2026-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2026-04-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04298203

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04298203, "Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT04298203. Licensed CC0.

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