# Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

> **NCT04300192** · PHASE4 · COMPLETED · sponsor: **Sanofi Pasteur, a Sanofi Company** · enrollment: 273 (actual)

## Conditions studied

- Pertussis Immunisation
- Diphtheria Immunisation
- Tetanus Immunisation
- Poliomyelitis Vaccine

## Interventions

- **BIOLOGICAL:** Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Combined with Inactivated Poliomyelitis Vaccine

## Key facts

- **NCT ID:** NCT04300192
- **Lead sponsor:** Sanofi Pasteur, a Sanofi Company
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-01-27
- **Primary completion:** 2023-01-11
- **Final completion:** 2023-01-11
- **Target enrollment:** 273 (ACTUAL)
- **Last updated:** 2025-09-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04300192

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04300192, "Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04300192. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*