# Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression

> **NCT04301271** · PHASE2 · COMPLETED · sponsor: **Charite University, Berlin, Germany** · enrollment: 161 (actual)

## Conditions studied

- Depressive Disorder, Major
- Obesity

## Interventions

- **DRUG:** Simvastatin 40mg
- **DRUG:** Placebo oral tablet

## Key facts

- **NCT ID:** NCT04301271
- **Lead sponsor:** Charite University, Berlin, Germany
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-08-13
- **Primary completion:** 2024-06-06
- **Final completion:** 2024-06-06
- **Target enrollment:** 161 (ACTUAL)
- **Last updated:** 2024-12-09

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04301271

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04301271, "Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04301271. Licensed CC0.

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