# Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression

> **NCT04301895** · PHASE1 · COMPLETED · sponsor: **University of California, San Francisco** · enrollment: 20 (actual)

## Conditions studied

- Opioid; Intoxication, Perception Disturbance (Acute)
- Acute Pain
- Overdose of Opiate
- Respiratory Depression
- Safety Issues

## Interventions

- **BEHAVIORAL:** Continuous conversational interaction
- **DRUG:** Remifentanil infusion

## Key facts

- **NCT ID:** NCT04301895
- **Lead sponsor:** University of California, San Francisco
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-04-30
- **Primary completion:** 2019-09-03
- **Final completion:** 2019-09-03
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2020-03-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04301895

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04301895, "Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04301895. Licensed CC0.

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