# Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI)

> **NCT04303325** · PHASE4 · RECRUITING · sponsor: **China Medical University, China** · enrollment: 72 (estimated)

## Conditions studied

- Depression

## Interventions

- **DRUG:** Esketamine
- **DRUG:** Saline Solution

## Key facts

- **NCT ID:** NCT04303325
- **Lead sponsor:** China Medical University, China
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-10-08
- **Primary completion:** 2024-10-30
- **Final completion:** 2024-12-30
- **Target enrollment:** 72 (ESTIMATED)
- **Last updated:** 2024-07-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04303325

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04303325, "Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04303325. Licensed CC0.

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