# Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases

> **NCT04307914** · NA · ACTIVE_NOT_RECRUITING · sponsor: **UMC Utrecht** · enrollment: 216 (estimated)

## Conditions studied

- Bone Metastases
- Bone Neoplasm
- Bone Lesion
- Bone Cancer
- Pain
- Cancer Induced Bone Pain
- Quality of Life
- Tumor
- Neoplasm Metastasis

## Interventions

- **RADIATION:** External beam radiotherapy
- **PROCEDURE:** MR-HIFU

## Key facts

- **NCT ID:** NCT04307914
- **Lead sponsor:** UMC Utrecht
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-03-10
- **Primary completion:** 2025-09-01
- **Final completion:** 2026-12-01
- **Target enrollment:** 216 (ESTIMATED)
- **Last updated:** 2026-03-05

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04307914

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04307914, "Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases". Retrieved via AI Analytics 2026-07-24 from https://api.ai-analytics.org/clinical/NCT04307914. Licensed CC0.

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