# IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone

> **NCT04313972** · PHASE4 · TERMINATED · sponsor: **Endeavor Health** · enrollment: 3 (actual)

## Conditions studied

- Interstitial Cystitis
- Painful Bladder Syndrome
- Bladder Pain Syndrome
- Low Dose Naltrexone
- Low-dose Naltrexone
- Naltrexone

## Interventions

- **DRUG:** low-dose naltrexone
- **DRUG:** Placebo oral tablet

## Key facts

- **NCT ID:** NCT04313972
- **Lead sponsor:** Endeavor Health
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2021-09-07
- **Primary completion:** 2023-01-23
- **Final completion:** 2023-02-23
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** There was a delay in recruitment initiation due to COVID-19 and internal logistical challenges. Following this delay, the principal investigator left the study site, and it was determined that the study should be terminated.
- **Last updated:** 2025-03-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04313972

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04313972, "IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04313972. Licensed CC0.

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