# Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

> **NCT04323046** · PHASE1 · RECRUITING · sponsor: **Sabine Mueller, MD, PhD** · enrollment: 20 (estimated)

## Conditions studied

- Glioblastoma
- Malignant Glioma
- Recurrent Glioblastoma
- Recurrent Malignant Glioma
- Recurrent Grade III Glioma
- Grade III Glioma

## Interventions

- **BIOLOGICAL:** Nivolumab
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT04323046
- **Lead sponsor:** Sabine Mueller, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-10-02
- **Primary completion:** 2026-03-01
- **Final completion:** 2029-03-01
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2025-05-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04323046

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04323046, "Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04323046. Licensed CC0.

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