# Methorexate and Knee Osteoarthritis

> **NCT04326894** · PHASE4 · COMPLETED · sponsor: **University of Alexandria** · enrollment: 128 (actual)

## Conditions studied

- Pain Reduction
- Physical Function Improvement

## Interventions

- **DRUG:** 25 mg/week oral methotrexate tablets
- **DRUG:** 25mg/week oral placebo tablets

## Key facts

- **NCT ID:** NCT04326894
- **Lead sponsor:** University of Alexandria
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-12
- **Primary completion:** 2012-12
- **Final completion:** 2012-12
- **Target enrollment:** 128 (ACTUAL)
- **Last updated:** 2020-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04326894

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04326894, "Methorexate and Knee Osteoarthritis". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT04326894. Licensed CC0.

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