# PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

> **NCT04329494** · PHASE1 · RECRUITING · sponsor: **City of Hope Medical Center** · enrollment: 49 (estimated)

## Conditions studied

- Clinical Stage IV Gastric Cancer AJCC v8
- Clinical Stage IVA Gastric Cancer AJCC v8
- Clinical Stage IVB Gastric Cancer AJCC v8
- Malignant Uterine Neoplasm
- Metastatic Appendix Carcinoma
- Metastatic Colorectal Carcinoma
- Metastatic Gastric Carcinoma
- Metastatic Malignant Neoplasm in the Peritoneum
- Metastatic Malignant Solid Neoplasm
- Metastatic Ovarian Carcinoma
- Pathologic Stage IV Gastric Cancer AJCC v8
- Peritoneal Carcinomatosis
- Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
- Stage IV Appendix Carcinoma AJCC v8
- Stage IV Colorectal Cancer AJCC v8
- Stage IV Ovarian Cancer AJCC v8
- Stage IV Uterine Corpus Cancer AJCC v8
- Stage IVA Appendix Carcinoma AJCC v8
- Stage IVA Colorectal Cancer AJCC v8
- Stage IVA Ovarian Cancer AJCC v8
- Stage IVA Uterine Corpus Cancer AJCC v8
- Stage IVB Appendix Carcinoma AJCC v8
- Stage IVB Colorectal Cancer AJCC v8
- Stage IVB Ovarian Cancer AJCC v8
- Stage IVB Uterine Corpus Cancer AJCC v8
- Stage IVC Appendix Carcinoma AJCC v8
- Stage IVC Colorectal Cancer AJCC v8

## Interventions

- **PROCEDURE:** Biopsy
- **DRUG:** Cisplatin
- **DRUG:** Doxorubicin
- **DRUG:** Fluorouracil
- **DEVICE:** Intraperitoneal Chemotherapy
- **DRUG:** Irinotecan
- **DRUG:** Leucovorin
- **DRUG:** Mitomycin
- **DRUG:** Oxaliplatin
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT04329494
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-08-21
- **Primary completion:** 2028-01-05
- **Final completion:** 2028-01-05
- **Target enrollment:** 49 (ESTIMATED)
- **Last updated:** 2025-12-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04329494

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04329494, "PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04329494. Licensed CC0.

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