# Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia

> **NCT04345289** · PHASE3 · TERMINATED · sponsor: **Thomas Benfield** · enrollment: 147 (actual)

## Conditions studied

- COVID
- Corona Virus Infection
- Viral Pneumonia

## Interventions

- **BIOLOGICAL:** Convalescent anti-SARS-CoV-2 plasma
- **OTHER:** Infusion placebo

## Key facts

- **NCT ID:** NCT04345289
- **Lead sponsor:** Thomas Benfield
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-05-01
- **Primary completion:** 2021-03-16
- **Final completion:** 2021-03-16
- **Target enrollment:** 147 (ACTUAL)
- **Why stopped:** DSMB advise due to high probability of futility
- **Last updated:** 2022-08-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04345289

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04345289, "Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04345289. Licensed CC0.

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