# SMILES: Study of Montelukast in Sickle Cell Disease

> **NCT04351698** · PHASE2,PHASE3 · UNKNOWN · sponsor: **Great Ormond Street Hospital for Children NHS Foundation Trust** · enrollment: 200 (estimated)

## Conditions studied

- Anemia, Sickle Cell
- Sleep-Disordered Breathing

## Interventions

- **DRUG:** Montelukast
- **OTHER:** Oral Placebo

## Key facts

- **NCT ID:** NCT04351698
- **Lead sponsor:** Great Ormond Street Hospital for Children NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-10-16
- **Primary completion:** 2024-09-30
- **Final completion:** 2024-09-30
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2023-11-01

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04351698

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04351698, "SMILES: Study of Montelukast in Sickle Cell Disease". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04351698. Licensed CC0.

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