# The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism

> **NCT04354896** · PHASE4 · COMPLETED · sponsor: **Insel Gruppe AG, University Hospital Bern** · enrollment: 322 (actual)

## Conditions studied

- Subclinical Hypothyroidism
- Sarcopenia

## Interventions

- **DRUG:** Levothyroxin
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04354896
- **Lead sponsor:** Insel Gruppe AG, University Hospital Bern
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-05
- **Primary completion:** 2018-05-04
- **Final completion:** 2018-05-04
- **Target enrollment:** 322 (ACTUAL)
- **Last updated:** 2023-05-18

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04354896

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04354896, "The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04354896. Licensed CC0.

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