# ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

> **NCT04363684** · — · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 2100 (estimated)

## Conditions studied

- Frontotemporal Lobar Degeneration (FTLD)
- Progressive Supranuclear Palsy (PSP)
- Corticobasal Degeneration (CBD)
- Behavioral Variant Frontotemporal Dementia (bvFTD)
- Semantic Variant Primary Progressive Aphasia (svPPA)
- Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
- FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)
- Amyotrophic Lateral Sclerosis
- Oligosymptomatic PSP (oPSP)
- C9orf72
- GRN Related Frontotemporal Dementia
- MAPT Gene Mutation
- TBK1 Gene Mutation
- Oligosymptomatic Progressive Supranuclear Palsy

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT04363684
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2020-03-01
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 2100 (ESTIMATED)
- **Last updated:** 2025-07-11

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04363684

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04363684, "ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT04363684. Licensed CC0.

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