# Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ

> **NCT04375605** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Universitätsmedizin Mannheim** · enrollment: 342 (actual)

## Conditions studied

- Gastroesophageal Junction Adenocarcinoma

## Interventions

- **DRUG:** 5-Fluorouracil
- **DRUG:** Calcium folinate
- **DRUG:** Oxaliplatin
- **DRUG:** Docetaxel
- **RADIATION:** Radiation
- **DRUG:** Oxaliplatin during radiotherapy
- **DRUG:** 5-Fluorouracil during radiotherapy

## Key facts

- **NCT ID:** NCT04375605
- **Lead sponsor:** Universitätsmedizin Mannheim
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-06-03
- **Primary completion:** 2025-12
- **Final completion:** 2025-12
- **Target enrollment:** 342 (ACTUAL)
- **Last updated:** 2025-01-07

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04375605

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04375605, "Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT04375605. Licensed CC0.

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