# Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN

> **NCT04379180** · — · UNKNOWN · sponsor: **Shandong University** · enrollment: 500 (estimated)

## Conditions studied

- Persistent Pulmonary Hypertension of the Newborn

## Interventions

- **DRUG:** Bosentan Tablets
- **DRUG:** Sildenafil Tablet
- **DRUG:** Tadalafil Tablets

## Key facts

- **NCT ID:** NCT04379180
- **Lead sponsor:** Shandong University
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2020-04-26
- **Primary completion:** 2023-02-26
- **Final completion:** 2023-05-30
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2020-05-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04379180

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04379180, "Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT04379180. Licensed CC0.

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