# COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia

> **NCT04381923** · NA · WITHDRAWN · sponsor: **University of Pennsylvania**

## Conditions studied

- Severe Acute Respiratory Syndrome Coronavirus 2
- Hypoxemic Respiratory Failure
- Pneumonia, Viral
- COVID

## Interventions

- **DEVICE:** Helmet Continuous Positive Airway Pressure (CPAP)
- **DEVICE:** High Flow Nasal Oxygen (HFNO)

## Key facts

- **NCT ID:** NCT04381923
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2021-11-15
- **Primary completion:** 2022-11-15
- **Final completion:** 2022-12-15
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Unable to obtain IRB approval
- **Last updated:** 2022-04-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04381923

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04381923, "COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT04381923. Licensed CC0.

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