Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer
Conditions
- Stage II Bladder Cancer AJCC v8
- Stage IIIA Bladder Cancer AJCC v8
- Muscle Invasive Bladder Carcinoma
Interventions
- DRUG: Cisplatin
- DRUG: Doxorubicin
- DRUG: Methotrexate
- BIOLOGICAL: Pegfilgrastim
- BIOLOGICAL: Pembrolizumab
- PROCEDURE: Radical Cystectomy
- DRUG: Vinblastine Sulfate
Sponsor
University of Washington
Collaborators