Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)

NCT04385277 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

41

Enrollment

NETWORK

Sponsor class

Conditions

Ganglioneuroblastoma, Nodular
Neuroblastoma

Interventions

PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Computed Tomography
BIOLOGICAL: Dinutuximab
PROCEDURE: FDG-Positron Emission Tomography
RADIATION: Iobenguane I-123
DRUG: Irinotecan
DRUG: Isotretinoin
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan
BIOLOGICAL: Sargramostim
DRUG: Temozolomide

Sponsor

Children's Oncology Group

Collaborators

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