# Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation

> **NCT04385771** · NA · SUSPENDED · sponsor: **Dr. Alexander Supady** · enrollment: 80 (estimated)

## Conditions studied

- Coronavirus Infection
- COVID
- SARS-CoV 2
- Respiratory Failure
- Cytokine Storm
- Extracorporeal Membrane Oxygenation

## Interventions

- **DEVICE:** vv-ECMO + cytokine adsorption (Cytosorb adsorber)
- **DEVICE:** vv-ECMO only (no cytokine adsorption)

## Key facts

- **NCT ID:** NCT04385771
- **Lead sponsor:** Dr. Alexander Supady
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** SUSPENDED
- **Start date:** 2020-09-01
- **Primary completion:** 2021-05-31
- **Final completion:** 2021-10-31
- **Target enrollment:** 80 (ESTIMATED)
- **Why stopped:** security concerns based on preliminary results from preceding CYCOV-I-study suggesting higer mortality in cytokine adsorption group
- **Last updated:** 2021-03-15

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04385771

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04385771, "Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04385771. Licensed CC0.

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