# Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI

> **NCT04391322** · — · ACTIVE_NOT_RECRUITING · sponsor: **The Hospital for Sick Children** · enrollment: 86 (estimated)

## Conditions studied

- Group 1: Healthy Controls
- Group 2: Stable CF
- Group 3: CF Participants Anticipated to Receive CFTR-modulator Therapy
- Group 4: 4-8 yo CF Participants Starting Triple Combination Modulator Therapy

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT04391322
- **Lead sponsor:** The Hospital for Sick Children
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-10-20
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 86 (ESTIMATED)
- **Last updated:** 2026-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04391322

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04391322, "Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT04391322. Licensed CC0.

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