# Pain Response Evaluation of a Combined Intervention to Cope Effectively

> **NCT04395001** · PHASE4 · COMPLETED · sponsor: **Wake Forest University Health Sciences** · enrollment: 280 (actual)

## Conditions studied

- Chronic Pain

## Interventions

- **DRUG:** duloxetine
- **BEHAVIORAL:** Web-based Cognitive Behavioral Therapy (CBT)
- **OTHER:** Nurse-delivered Motivational Interviewing

## Key facts

- **NCT ID:** NCT04395001
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-02-24
- **Primary completion:** 2024-07-18
- **Final completion:** 2024-07-18
- **Target enrollment:** 280 (ACTUAL)
- **Last updated:** 2025-10-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04395001

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04395001, "Pain Response Evaluation of a Combined Intervention to Cope Effectively". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT04395001. Licensed CC0.

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