# 5-HTP and Creatine for Depression

> **NCT04395183** · PHASE2 · COMPLETED · sponsor: **University of Utah** · enrollment: 43 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** 5-Hydroxytryptophan 100 MG
- **DRUG:** Creatine monohydrate
- **DRUG:** placebo matched to 5-HTP
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04395183
- **Lead sponsor:** University of Utah
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-03-01
- **Primary completion:** 2023-08-01
- **Final completion:** 2024-03-01
- **Target enrollment:** 43 (ACTUAL)
- **Last updated:** 2024-07-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04395183

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04395183, "5-HTP and Creatine for Depression". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04395183. Licensed CC0.

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