# GM1 Prophylaxis for WBRT Related Cognitive Dysfunction

> **NCT04395339** · PHASE3 · TERMINATED · sponsor: **Sun Yat-sen University** · enrollment: 51 (actual)

## Conditions studied

- Brain Metastases
- Radiotherapy Side Effect
- Cognitive Impairment
- Gangliosidosis, GM1
- Breast Cancer

## Interventions

- **DRUG:** Monosialotetrahexosyl ganglioside (GM1)
- **DRUG:** Control

## Key facts

- **NCT ID:** NCT04395339
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-05-15
- **Primary completion:** 2024-07-31
- **Final completion:** 2024-07-31
- **Target enrollment:** 51 (ACTUAL)
- **Why stopped:** Difficulty accruing subjects the study accrual was closed
- **Last updated:** 2024-08-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04395339

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04395339, "GM1 Prophylaxis for WBRT Related Cognitive Dysfunction". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04395339. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*