# Gemcitabine for the Prevention of Intravesical Recurrence of Urothelial Cancer in Patients With Upper Urinary Tract Urothelial Cancer Undergoing Radical Nephroureterectomy, GEMINI Study

> **NCT04398368** · PHASE2 · TERMINATED · sponsor: **Mayo Clinic** · enrollment: 25 (actual)

## Conditions studied

- Stage 0a Renal Pelvis and Ureter Cancer AJCC v8
- Stage 0a Renal Pelvis Cancer AJCC v8
- Stage 0a Ureter Cancer AJCC v8
- Stage 0is Renal Pelvis and Ureter Cancer AJCC v8
- Stage 0is Renal Pelvis Cancer AJCC v8
- Stage 0is Ureter Cancer AJCC v8
- Stage I Renal Pelvis and Ureter Cancer AJCC v8
- Stage I Renal Pelvis Cancer AJCC v8
- Stage I Ureter Cancer AJCC v8
- Stage II Renal Pelvis and Ureter Cancer AJCC v8
- Stage II Renal Pelvis Cancer AJCC v8
- Stage II Ureter Cancer AJCC v8
- Stage III Renal Pelvis and Ureter Cancer AJCC v8
- Stage III Renal Pelvis Cancer AJCC v8
- Stage III Ureter Cancer AJCC v8
- Stage IV Renal Pelvis and Ureter Cancer AJCC v8
- Stage IV Renal Pelvis Cancer AJCC v8
- Stage IV Ureter Cancer AJCC v8

## Interventions

- **DRUG:** Gemcitabine Hydrochloride

## Key facts

- **NCT ID:** NCT04398368
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2020-06-05
- **Primary completion:** 2023-02-02
- **Final completion:** 2023-02-02
- **Target enrollment:** 25 (ACTUAL)
- **Why stopped:** Focus research efforts on other projects.
- **Last updated:** 2023-08-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04398368

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04398368, "Gemcitabine for the Prevention of Intravesical Recurrence of Urothelial Cancer in Patients With Upper Urinary Tract Urothelial Cancer Undergoing Radical Nephroureterectomy, GEMINI Study". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04398368. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*