# Buspirone and Melatonin for Depression Following Traumatic Brain Injury

> **NCT04400266** · PHASE4 · RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 10 (estimated)

## Conditions studied

- Depression
- Brain Injuries, Traumatic

## Interventions

- **DRUG:** Buspirone
- **DRUG:** Mealatonin

## Key facts

- **NCT ID:** NCT04400266
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-08-01
- **Primary completion:** 2028-07-31
- **Final completion:** 2028-07-31
- **Target enrollment:** 10 (ESTIMATED)
- **Last updated:** 2026-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04400266

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04400266, "Buspirone and Melatonin for Depression Following Traumatic Brain Injury". Retrieved via AI Analytics 2026-05-20 from https://api.ai-analytics.org/clinical/NCT04400266. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*