# Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency

> **NCT04404400** · PHASE3 · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 1092 (estimated)

## Conditions studied

- Critical Illness Related Corticosteroids Insufficiency

## Interventions

- **DRUG:** Investigational products administration
- **DRUG:** Placebo administration

## Key facts

- **NCT ID:** NCT04404400
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-02-17
- **Primary completion:** 2026-02
- **Final completion:** 2026-02
- **Target enrollment:** 1092 (ESTIMATED)
- **Last updated:** 2025-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04404400

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04404400, "Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency". Retrieved via AI Analytics 2026-09-03 from https://api.ai-analytics.org/clinical/NCT04404400. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*