# Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age

> **NCT04405180** · PHASE2 · COMPLETED · sponsor: **Gladwin, Mark, MD** · enrollment: 64 (actual)

## Conditions studied

- Aging
- Sedentary Lifestyle
- Frailty

## Interventions

- **DRUG:** Placebos
- **DRUG:** 20mg sodium nitrite tid

## Key facts

- **NCT ID:** NCT04405180
- **Lead sponsor:** Gladwin, Mark, MD
- **Sponsor class:** INDIV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-04-23
- **Primary completion:** 2023-07-14
- **Final completion:** 2023-07-14
- **Target enrollment:** 64 (ACTUAL)
- **Last updated:** 2024-10-10

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04405180

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04405180, "Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04405180. Licensed CC0.

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