# D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

> **NCT04411199** · PHASE3 · COMPLETED · sponsor: **PolyPid Ltd.** · enrollment: 800 (actual)

## Conditions studied

- Surgical Site Infection
- Colon Surgery
- Abdominal Surgery
- Post-Op Infection

## Interventions

- **DRUG:** D-PLEX
- **OTHER:** Standard of Care (SoC)

## Key facts

- **NCT ID:** NCT04411199
- **Lead sponsor:** PolyPid Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-12-15
- **Primary completion:** 2025-04-14
- **Final completion:** 2025-05-10
- **Target enrollment:** 800 (ACTUAL)
- **Last updated:** 2025-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04411199

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04411199, "D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT04411199. Licensed CC0.

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