# Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer

> **NCT04418089** · PHASE2 · COMPLETED · sponsor: **Indonesia University** · enrollment: 60 (actual)

## Conditions studied

- Breast Cancer
- Chemotherapy Effect

## Interventions

- **DRUG:** Simvastatin 40mg
- **DRUG:** Placebo oral capsule

## Key facts

- **NCT ID:** NCT04418089
- **Lead sponsor:** Indonesia University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-01-15
- **Primary completion:** 2019-05-20
- **Final completion:** 2019-09-05
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2020-06-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04418089

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04418089, "Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT04418089. Licensed CC0.

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