# Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus

> **NCT04418999** · EARLY_PHASE1 · COMPLETED · sponsor: **Illinois College of Optometry** · enrollment: 36 (actual)

## Conditions studied

- Keratoconus
- Dry Eye
- Allergy

## Interventions

- **DRUG:** dexamethasone ophthalmic insert 0.4 mg, for intracanalicular use
- **DRUG:** Loteprednol Etabonate 0.38% Ophthalmic Gel/Jelly

## Key facts

- **NCT ID:** NCT04418999
- **Lead sponsor:** Illinois College of Optometry
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-09-01
- **Primary completion:** 2021-12-31
- **Final completion:** 2021-12-31
- **Target enrollment:** 36 (ACTUAL)
- **Last updated:** 2025-04-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04418999

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04418999, "Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04418999. Licensed CC0.

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