# Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction

> **NCT04423276** · PHASE4 · UNKNOWN · sponsor: **RenJi Hospital** · enrollment: 360 (estimated)

## Conditions studied

- Total Knee Arthroplasty
- Fracture of Head of Femur Articular Displaced
- Protrusion of Intervertebral Disc

## Interventions

- **DRUG:** Donepezil
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04423276
- **Lead sponsor:** RenJi Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2020-06-14
- **Primary completion:** 2021-12-01
- **Final completion:** 2022-12-01
- **Target enrollment:** 360 (ESTIMATED)
- **Last updated:** 2020-12-29

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04423276

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04423276, "Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction". Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/clinical/NCT04423276. Licensed CC0.

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