# Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

> **NCT04431024** · — · RECRUITING · sponsor: **National Cancer Institute (NCI)** · enrollment: 800 (estimated)

## Conditions studied

- Familial Cancer
- BRCA1-Associated Protein-1 (BAP1) Mutations
- Tumor Predisposition Syndrome (TPDS)
- Mesothelioma

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT04431024
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2021-03-30
- **Primary completion:** 2038-06-30
- **Final completion:** 2038-06-30
- **Target enrollment:** 800 (ESTIMATED)
- **Last updated:** 2026-05-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04431024

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04431024, "Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04431024. Licensed CC0.

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