# An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

> **NCT04442295** · PHASE1,PHASE2 · COMPLETED · sponsor: **Stoke Therapeutics, Inc** · enrollment: 62 (actual)

## Conditions studied

- Dravet Syndrome

## Interventions

- **DRUG:** STK-001 - Single Ascending Doses
- **DRUG:** STK-001 - Multiple Ascending Doses

## Key facts

- **NCT ID:** NCT04442295
- **Lead sponsor:** Stoke Therapeutics, Inc
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-06-29
- **Primary completion:** 2023-11-14
- **Final completion:** 2023-11-14
- **Target enrollment:** 62 (ACTUAL)
- **Last updated:** 2025-05-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04442295

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04442295, "An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT04442295. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*