# Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

> **NCT04454203** · PHASE4 · RECRUITING · sponsor: **Duke University** · enrollment: 40 (estimated)

## Conditions studied

- Tourniquet Hypertension
- Intraoperative Hypertension
- Total Ankle Arthroplasty
- Ankle Fusion

## Interventions

- **DRUG:** Mepivacaine
- **DRUG:** Saline
- **PROCEDURE:** Perifemoral Injection of Local Anesthetic
- **PROCEDURE:** Perifemoral Injection of Local Anesthetic

## Key facts

- **NCT ID:** NCT04454203
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-02-05
- **Primary completion:** 2027-02-01
- **Final completion:** 2027-02-03
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-03-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04454203

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04454203, "Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT04454203. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*