# The Use of Penicillin Allergy Clinical Decision Rule to Enable Direct Oral Penicillin Challenge

> **NCT04454229** · NA · COMPLETED · sponsor: **Austin Health** · enrollment: 382 (actual)

## Conditions studied

- Hypersensitivity, Immediate
- Hypersensitivity, Delayed
- Hypersensitivity Response

## Interventions

- **OTHER:** Direct oral penicillin challenge
- **OTHER:** Standard of care

## Key facts

- **NCT ID:** NCT04454229
- **Lead sponsor:** Austin Health
- **Sponsor class:** OTHER_GOV
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-01
- **Primary completion:** 2022-12-02
- **Final completion:** 2022-12-02
- **Target enrollment:** 382 (ACTUAL)
- **Last updated:** 2023-03-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04454229

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04454229, "The Use of Penicillin Allergy Clinical Decision Rule to Enable Direct Oral Penicillin Challenge". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04454229. Licensed CC0.

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