# Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder

> **NCT04454411** · PHASE2 · TERMINATED · sponsor: **University of Pennsylvania** · enrollment: 3 (actual)

## Conditions studied

- Opioid Dependence

## Interventions

- **DRUG:** Brixadi
- **DRUG:** Vivitrol

## Key facts

- **NCT ID:** NCT04454411
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2022-08-01
- **Primary completion:** 2024-08-31
- **Final completion:** 2024-08-31
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** Primary funding source has ended.
- **Last updated:** 2025-08-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04454411

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04454411, "Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04454411. Licensed CC0.

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