# Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury

> **NCT04458324** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Spaulding Rehabilitation Hospital** · enrollment: 70 (estimated)

## Conditions studied

- Spinal Cord Injuries

## Interventions

- **DRUG:** Buspirone Hydrochloride
- **DRUG:** Buspirone placebo
- **DEVICE:** Noninvasive Ventilation (NIV)
- **DEVICE:** Sham Non-invasive ventilation (NIV)
- **OTHER:** Functional Electrical Stimulation Row Training (FESRT)

## Key facts

- **NCT ID:** NCT04458324
- **Lead sponsor:** Spaulding Rehabilitation Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-12-22
- **Primary completion:** 2026-07-31
- **Final completion:** 2027-07-31
- **Target enrollment:** 70 (ESTIMATED)
- **Last updated:** 2026-03-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04458324

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04458324, "Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04458324. Licensed CC0.

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