# Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen

> **NCT04459117** · PHASE2,PHASE3 · COMPLETED · sponsor: **Institut National de la Santé Et de la Recherche Médicale, France** · enrollment: 804 (actual)

## Conditions studied

- Patency of the Ductus Arteriosus
- Acetaminophen
- Extreme Prematurity

## Interventions

- **DRUG:** Acetaminophen
- **DRUG:** NACL 0.9%

## Key facts

- **NCT ID:** NCT04459117
- **Lead sponsor:** Institut National de la Santé Et de la Recherche Médicale, France
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-10-29
- **Primary completion:** 2024-06-20
- **Final completion:** 2024-06-20
- **Target enrollment:** 804 (ACTUAL)
- **Last updated:** 2026-03-16

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04459117

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04459117, "Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04459117. Licensed CC0.

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