# Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study

> **NCT04465123** · PHASE3 · UNKNOWN · sponsor: **Chiang Mai University** · enrollment: 100 (estimated)

## Conditions studied

- Acute Heart Failure
- Acute Kidney Injury

## Interventions

- **DRUG:** Spironolactone or hydrochlorothiazide
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04465123
- **Lead sponsor:** Chiang Mai University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2020-08-13
- **Primary completion:** 2022-07-31
- **Final completion:** 2022-12-31
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2020-08-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04465123

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04465123, "Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04465123. Licensed CC0.

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