# Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation

> **NCT04467164** · NA · COMPLETED · sponsor: **Massachusetts General Hospital** · enrollment: 20 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **OTHER:** exhalatory-gated transcutaneous vagus nerve stimulation (e-RAVANS)
- **OTHER:** Inhalatory-gated transcutaneous vagus nerve stimulation (i-RAVANS)

## Key facts

- **NCT ID:** NCT04467164
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-04-15
- **Primary completion:** 2018-09-15
- **Final completion:** 2018-09-22
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2025-03-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04467164

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04467164, "Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT04467164. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*