# Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of KPL-404 in Healthy Subjects

> **NCT04497662** · PHASE1 · COMPLETED · sponsor: **Kiniksa Pharmaceuticals, Ltd.** · enrollment: 52 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** KPL-404
- **OTHER:** Matching Placebo

## Key facts

- **NCT ID:** NCT04497662
- **Lead sponsor:** Kiniksa Pharmaceuticals, Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-10-22
- **Primary completion:** 2021-01-21
- **Final completion:** 2021-03-02
- **Target enrollment:** 52 (ACTUAL)
- **Last updated:** 2021-05-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04497662

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04497662, "Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of KPL-404 in Healthy Subjects". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04497662. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*