# Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer

> **NCT04505553** · PHASE2 · COMPLETED · sponsor: **University of Washington** · enrollment: 78 (actual)

## Conditions studied

- Appendix Carcinoma
- Colon Carcinoma
- Esophageal Carcinoma
- Gastric Carcinoma
- Liver and Intrahepatic Bile Duct Carcinoma
- Malignant Digestive System Neoplasm
- Pancreatic Carcinoma
- Rectal Carcinoma
- Small Intestinal Carcinoma
- Anal Carcinoma
- Digestive System Carcinoma
- Digestive System Neuroendocrine Tumor
- Pancreatic Neuroendocrine Tumor

## Interventions

- **PROCEDURE:** Acupuncture Therapy
- **PROCEDURE:** Acupressure Therapy
- **PROCEDURE:** Oral Cryotherapy
- **OTHER:** Questionnaire Administration
- **OTHER:** Quality-of-Life Assessment

## Key facts

- **NCT ID:** NCT04505553
- **Lead sponsor:** University of Washington
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-06-01
- **Primary completion:** 2024-03-07
- **Final completion:** 2024-03-31
- **Target enrollment:** 78 (ACTUAL)
- **Last updated:** 2026-01-21

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04505553

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04505553, "Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04505553. Licensed CC0.

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